Mouse models of madness
نویسندگان
چکیده
منابع مشابه
Dopamine Receptor Excess and Mouse Madness
The dopamine hypothesis of schizophrenia is based on evidence that the major antipsychotic drugs act by blocking dopamine D2 receptors and that dopamine-releasing drugs worsen symptoms. In this issue of Neuron, Kellendonk et al. report an elegant conditional transgenic mouse overexpressing dopamine D2 receptors selectively in the striatum. Strikingly, these animals display selective cognitive i...
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Background and aim: Madness is a subject that has long been the subject of legal attention. Today, Industrial societies are confronted with a phenomenon called mental disorders and those with such disease which unfortunately is increasing day by day. Obviously, laws over time for scientific advances need to be reformed. This article explores the legal status and the way in which mental patients...
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The patient had only minor shortness of breath upon climbing two flights of stairs, despite a left ventricular ejection fraction of 30%. He was stable and doing well on digoxin, diuretics, beta blockers and an angiotensinconverting enzyme (ACE) inhibitor. However, a troublesome dry cough was becoming intolerable to the patient. After discussion with him, we elected to consider a trial of an ang...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 1999
ISSN: 1359-4184,1476-5578
DOI: 10.1038/sj.mp.4000577